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Iron Deficiency Anemia in Children

Updated: Sep 6, 2020

Original research by Jelena Roganovic and Ksenija Starinac; Abstract written by Ifunanya Onyima, MS, RD




Iron is a micronutrient that serves several purposes within the human body. This peer-reviewed article reviews the importance of adequate iron via food and supplements and the effects of iron deficiency in children. These effects include many negatives outcomes to numerous parts of the brain. This article is a meta-analysis; 93 scientific studies were cited throughout.


“One study found higher instances of brain-related auditory and visual dysfunction in the experimental group (children with iron-deficiency anemia) when compared to the control group (children who did not have iron-deficiency anemia). ”

Decreased expression of dopamine, decreased/disrupted/impaired myelination and disruption of neural enzyme function are a few examples of the negative health outcomes that are associated with iron deficiency. One study found higher instances of brain-related auditory and visual dysfunction in the experimental group (children with iron-deficiency anemia) when compared to the control group (children who did not have iron-deficiency anemia). Pagophagia, a sub-set of PICA, is common amongst iron-deficient children. This condition could lead to malnutrition and other illnesses, which could further brain maldevelopment and dysfunction.


Iron deficiency is very common around the world, making the illness easy to study and examine. This leads to extensive research on the topic, resulting in a general consensus that is supported by sufficient research and is healthy for most people. Iron supplementation paired with dietary modifications are the primary treatment methods for iron deficiency.


This analysis is satisfactory – several research studies from around the world were succinctly summarized to illustrate brain-related health risks associated with iron deficiency.



Source(s)

Roganović, Jelena, and Ksenija Starinac. “Iron Deficiency Anemia in Children.” Current Topics in Anemia, February 7, 2018. https://doi.org/10.5772/intechopen.69774.


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